- Uncommon process of skin necrosis and ulcers
- Associated w/calcification of small & medium sized arteries
- Chronic kidney failure w/patients typically on dialysis
- Elevation in calcium, phosphorous and PTH can contribute
- Diabetes, obesity
- Initial skin finding of painful plaque, nodule, indurated area, other
- Then progressive, severely painful skin ulcers and necrosis
- Typically multiple
- Most commonly thighs, abdomen, buttocks; but can affect other areas
- Poorly healing wounds
- Associated w/high mortality
- Initial skin finding of painful plaque, nodule, indurated area, other
- Then often multiple, very painful skin ulcers and necrosis, often w/black eschar
- Can become infected, in which case associated inflammatory findings
- May have palpable, calcified sub-cutaneous nodules
- Skin biopsy if diagnosis unclear and/or need to rule out other causes